Simulations of Biological Systems
Multi-Physics Models of Cancer Cells
Inverse Solutions for Electric and Potential Field Imaging|
C.R. Johnson, R.S. MacLeod. In Physiological Imaging, Spectroscopy, andEarlyDetection Diagnostic Methods, Vol. 1887, Edited by R.L. Barbour and M.J. Carvlin, SPIE, pp. 130--139. 1993.
Visualization of Bioelectric Fields|
R.S. MacLeod, C.R. Johnson, M.A. Matheson. In IEEE Computer Graphics and Applications, Vol. 14, pp. 10--12. Jul, 1993.
A 3D Cellular Automata Model of the Heart|
P.B. Gharpure, C.R. Johnson. In IEEE Engineering in Medicine and Biology Society 15th Annual International Conference, IEEE Press, pp. 752--753. 1993.
Computer Simulations Reveal Complexity of Electrical Activity in the Human Thorax|
C.R. Johnson, R.S. MacLeod, M.A. Matheson. In Computers in Physics, Vol. 6, pp. 230--237. May/June, 1992.
Localization of Ischemia during Coronary Angioplasty using Body Surface Potential Mapping and an Electrocardiographic Inverse Solution|
R.S. MacLeod, C.R. Johnson, M.J. Gardner B.M.. In Computers in Cardiology, IEEE Press, pp. 251--254. 1992.
Effects of Anistropy and Inhomogeneity on Electrocardiographic Fields: A Finite Element Study|
C.R. Johnson, R.S. MacLeod, A. Dutson. In Engineering in Medicine and Biology Society 14th Annual International Conference, IEEE Press, pp. 2009--2010. 1992.
Visualization of cardiac bioelectricity --- a case study|
R.S. MacLeod, C.R. Johnson, M.A. Matheson. In IEEE Visualization `92, pp. 411--418. 1992.
Visualization Tools for Computational Electrocardiology|
R.S. MacLeod, C.R. Johnson, M.A. Matheson. In Visualization in Biomedical Computing, pp. 433--444. 1992.
A Computer Model for the Study of Electrical Current Flow in the Human Thorax|
C.R. Johnson, R.S. MacLeod, P.R. Ershler. In Computers in Biology and Medicine, Vol. 22, No. 5, Elsevier BV, pp. 305--323. 1992.
Electrocardiography has played an important role in the detection and characterization of heart function, both in normal and abnormal states. In this paper we present an inhomogeneous, anisotropic computer model of the human thorax for use in electrocardiography with emphasis on the calculation of transthoracic potential and current distributions. Knowledge of the current pathways in the thorax has many applications in electrocardiography and has direct utility in studies pertaining to cardiac defibrillation, forward and inverse problems, impedance tomography, and electrode placement in electrocardiography.
Keywords: scalar field methods, vector field methods, tensor field methods, cardiac heart, scientific visualization
Computational Studies of Forward and Inverse Problems in Electrocardiology|
C.R. Johnson, R.S. MacLeod. In Biomedical Modeling and Simulation, Edited by J. Eisenfeld and D.S. Levine and M. Witten, Elsevier Science Publishers, Elsevier, Amsterdam pp. 283--290. 1992.
Nonuniform Spatial Mesh Adaption Using a Posteriori Error Estimate: Applications to Forward and Inverse Problems|
C.R. Johnson, R.S. MacLeod. In Adaptive Methods for Partial Differential Equations, Vol. 14, Edited by J.E. Flaherty and M.S. Shephard, Elsevier, pp. 311--326. 1992.
Computer Models for Calculating Transthoracic Current Flow|
C.R. Johnson, R.S. MacLeod. In IEEE Engineering in Medicine and Biology Society 13th Annual International Conference, IEEE Press, pp. 768--769. 1991.
Construction of an Inhomogeneous Model of the Human Torso for Use in Computational Electrocardiography|
R.S. MacLeod, C.R. Johnson, P.R. Ershler. In IEEE Engineering in Medicine and Biology Society 13th Annual International Conference, IEEE Press, pp. 688--689. 1991.
Electrical Activation of the Heart: Computational Studies of the Forward and Inverse Problems in Electrocardiography|
C.R. Johnson, A.E. Pollard. In Computer Assisted Analysis and Modeling, MIT Press, pp. 583--628. 1990.